Optimization and Process Simulation | Ultrafiltration …
During optimization trials, it is important to choose an appropriate combination of feed flow rate and TMP to maximize flux. This will minimize process time and/or membrane area, allowing for optimal membrane area and pump sizing (minimal holdup due to pump sizing as well as pump passes). ... Tangential Flow Filtration: Fluid is pumped ...
The intelligent prediction of membrane fouling during …
The relationship between the microstructure of the fouled membrane and the depth filtration model is shown in Fig. 1 b. In the, ... (GA) and particle swarm algorithm (PSO) are the two main optimization methods of AI models that are commonly used in membrane fouling analysis (Tao and Li, 2018; Yao et al., 2022). In predicting membrane …
Adsorptive dynamic membrane for water purification: Model and optimization
Abstract. Adsorptive dynamic membrane, consisting of adsorption and filtration, exhibits a desirable efficiency for water purification. However, the entire adsorption-filtration process is affected by many influencing factors, and the operating regulation and process optimization remain still uncertain. The present work deals with …
Designing optimally‐graded depth filter media using a novel multiscale
When simulating depth filtration, models for the interaction of fluid and dispersed particles as well as between particles and the surfaces of the filter material are incorporated. 18, ... Future work could address this issue by fitting an advanced model on the CS. 35 Also the optimization goal could be changed. We here focused on …
Design and optimization of Single Pass Tangential Flow Filtration …
Most of the model calculations were performed using modules having similar properties to those of commercially available Pellicon® 3 cassettes with Ultracel 30 kDa membranes and C screen (MilliporeSigma, Bedford, MA) which have a mesh length of 500 μm and hydraulic diameter of 100 μm [13].Model simulations were focused on exploring …
Model-based optimization approaches for pressure-driven …
Filtration models. The primary goal of filtration models used in process optimization is to predict the outcome of a membrane process with known process parameters at given feed values. In a steady-state condition, this prediction can be done by solving general mass balances for both overall streams (Fig. 1 a) and each component …
Integrated Filtration and Washing Modeling: Optimization …
A mechanistic workflow for the optimization of an integrated filtration and washing model minimized impurities in the isolated cake. This workflow procedure first estimates product and process characteristics (e.g., particle sphericity, porosity, cake and medium resistance, and cake compressibility) using a gPROMS FormulatedProducts …
(206a) Scale-up and Optimization of Filtration Processes: …
observed in the optimization objective will also be outlined. This filtration workflow for scale-up outlined above was applied in this work for a number of industrial cases, involving compressible cakes. This model-based approach allows the filtration unit step to be scaled-up and optimized in a fast and efficient
Book: Optimization Models
Optimization Models. Optimization Models. G.C. Calafiore and L. El Ghaoui. Cambridge University Press. October 2014. Publisher's book web site. Emphasizing practical understanding over the technicalities of specific algorithms, this elegant textbook is an accessible introduction to the field of optimization, focusing on …
Modeling and Simulation of Filtration Processes
Approaches for the microscale (pore scale) and macroscale (filter element scale) investigation of filtration processes are discussed in detail, along with a recently …
Modelling and optimization study to improve the filtration …
In this model, the F-value of about 23.7 for the filtration efficiency (n) and their respective p-value is about less than the required value of 0.05 which demonstrates that the model is acceptable which can be used for the optimization and further analysis.
Drying Process Optimization for an API Solvate Using Heat …
In order to formulate a model, it is useful to define the various steps in the drying process. Figure 3 shows the schematic of various rate processes, along with their interactions that form the basis of the drying model used for simulation and optimization. Phase I consists of evaporation of the unbound solvent, which is relatively fast and can …
Integrated Filtration and Washing Modeling: …
A mechanistic workflow for the optimization of an integrated filtration and washing model minimized impurities in the isolated cake. This workflow procedure …
A filtration model for prediction of local flux distribution …
A filtration mathematical model was developed on the basis of complete mass balance and momentum balance for the local flux distribution prediction and optimization of submerged hollow fiber membrane module.
Modeling and simulation for design and analysis of …
State-of-the-art simulation for pervaporation, membrane distillation, membrane filtration, membrane reactors, ... (2016) proposed a five-step process customized for simulators asmodel development, validation, model solution, optimization methods and programs, interfacing with a process simulator, and membrane …
Orthogonal experimental design and parameter optimization …
A regression model of influence on pressure drop and filtration efficiency under multi-factor conditions is established to build a relationship between pressure drop, filtration efficiency, and control parameters. • An optimization constraint function based on a non-dominated sorting genetic algorithm (NSGA-II) is established. •
Combined mechanism fouling model and method for optimization …
Of the four classical models, the standard model is the most frequently used as it forms the basis for the widely used V max sizing method [11].Models that combine two or more classical blocking mechanisms have been shown to be useful where filters foul by more than one mechanism, either simultaneously or sequentially [12], [13], [14].However, …
Model-based optimization approaches for pressure …
Summary of representative ML-based models for pressure-driven membrane applications, which include microfiltration (MF), ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO). Fouling is a significant problem in …
Model-Based Design and Process Optimization of
In this study the Single-Pass-Tangential-Flow-Filtration (SPTFF) concept for continuous ultrafiltration in bioprocessing is investigated. Based on a previously validated physico-chemical model for ...
Model and optimization of electromagnetic filtration of …
Model and optimization of electromagnetic filtration of metals. S. Golak, R. Zagorski Silesian University of Technology, Faculty of Materials Engineering and Metallurgy, Katowice, Poland Electromagnetic buoyancy force causes the mo vement of nonconducive par ticles in a c onducting liquid under electromagnetic fi eld.
CFD Simulation of the Filtration Performance of Fibrous …
Aiming at disclosing the quantitative effects of Coulomb forces on the filtration efficiency of aerosol particles, a three-dimensional random fiber model was established to describe the microstructure of fibrous filters. Then, computational models including the flow model, particle model, and electric field model were constructed to …
A review of coagulation explaining its definition
Furthermore, it discusses the models and optimization techniques used for the coagulation process including response surface methodology (RSM), ar-tificial neural network (ANN), and several metaheuristic algorithms combined with ANN and RSM for optimization in previous work. The ANN model has more accurate results than RSM.
Optimization and Process Simulation | Ultrafiltration …
Optimization and Process Simulation. Request Information. Optimization & Process Simulation for Ultrafiltration. Before you implement an ultrafiltration step, define these key operation parameters: Crossflow …
Data-based modeling and optimization of a hybrid column …
Lack of robust techniques for optimization of hybrid separation systems is obvious in the literature. A novel hybrid approach for modeling and optimization of a hybrid process consisting of fixed-bed adsorption column (FBAC) and dead-end filtration (DEF) for the removal of methylene blue from water was presented.
Cake Filtration
Model-assisted analyses and interpretation of experimental data, and optimization and simulation of the filtration processes are of continuing interest. The majority of the previous modeling efforts have been limited to linear filtration applications, in spite of the fact that many filtration processes involve radial filtration applications.
Experimental study and optimization on filtration and …
Under the investigated filtration superficial velocity region, the average filtration efficiency is enhanced 3.23% and the pressure drop is reduced 49.94%; compared to model B (granules size of 5 mm), although the pressure drop increases about 28.91%, the average filtration efficiency is enhanced about 9.22%.
An Intelligent Optimization Model Analysis and …
Currently clean water treatment technology is in-need to optimize available environmental–friendly bio-filtration technology as means for pre-treatment of raw water quality improvement with the intelligent computational …
Single pass tangential flow filtration: Critical operational …
1. Introduction. Membrane processes are widely used in the separation and purification of biological products [1], [2].Filtration, specifically microfiltration (MF) and ultrafiltration (UF), is a key unit operation in virtually every downstream process of biopharmaceutical production [3], [4].Filtration processes find application where many …
An intelligent optimization model analysis and …
In this paper, optimization model of bio-filtration was simulated by using Process Hierarchy Diagram (PHD) and Business Process Modeling and Notation …
Model-Based Design and Process Optimization of …
In this study the Single-Pass-Tangential-Flow-Filtration (SPTFF) concept for continuous ultrafiltration in bioprocessing is investigated. Based on a previously validated physico-chemical model for a single ultrafiltration cassette, the transfer to a multistage SPTFF is predicted and validated experimentally by concentration steps for bovine …
